Category: News || File ID: 71 || Last changed on: 2009-09-10 08:56:23+01

CASIMIR Report of data and resource sharing for mouse functional genomics

Sharing the fruits of research in the biomedical sciences is critical for the advance of knowledge, yet with the advent of large-scale data gathering following the completion of the genome projects this is becoming harder to facilitate and more difficult to monitor, as reported in Nature today.

The results of a meeting on data and resource sharing organised by CASIMIR are reported in today’s Nature.

The meeting was attended by senior representatives of major international research sponsors, leading scientific journals, intellectual property and technology transfer specialists and sociologists. It endorsed the need for global coordination and effective policies to reduce barriers to the free exchange of data and materials between scientists to ensure the sharing of research results and materials to maximize research benefit, optimize the use of research sponsorship and more effectively manage and optimize the dissemination of biological research results through academic or commercial channels.

Significant consensus was achieved, and the results of this important meeting are published in Nature this week. Research on mice as models for human diseases is of major current international importance and is essential until better alternatives are found if the full societal benefits of the elucidation of the human genome are to be achieved. Better sharing of data and existing mice will reduce the need to generate new model organisms and avoid unnecessary duplication.

One of the key findings of this study is the negative impact of over-restrictive licensing by some Universities and research agencies of genetically engineered mice and embryonic stem cells - the outputs of this research - and the failure of researchers to efficiently share their research results and materials by depositing their mice and ES cells in the major public repositories now in place in Europe, North America, Japan and Australia.

The meeting set an agenda for community discussion - The Rome Agenda - also free to access online, which outlines guidelines to enable sharing of biomaterials under the least restrictive terms, avoiding restrictive material transfer agreements (MTAs) where possible. The meeting also recommended increased investment in public databases and mouse repositories to keep pace with the rapid acceleration of research in this area.

The Rome Agenda is intended to spark community discussion on this subject. Paul Schofield, Tania Bubela (University of Alberta, Edmonton, Canada) and other meeting participants will respond to reader comments in an online forums on Nature Network.

Please click here for background documents and presentations from the meeting:
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