Category: Meetings || File ID: 72 || Last changed on: 2009-11-19 15:45:07

Database & Bioresource Sustainability Models

Rome 11th – 12th November 2009

Aims of the meeting:

The meeting sets out to examine the issue of long-term, primarily financial, sustainability for databases and biorepositories – mainly, but not exclusively, those containing ES cells and mice. We will examine a range of databases and resources which have had varying degrees of success with maintaining their activities and using different business models, to see if we can find a consensus on what kind of business models work, what don"t work and what might work in the future. One key issue is whether resources will ever be viable without core support at least from not-for-profit funding agencies and organisations, how stable that funding needs to be and what the criteria are for maintaining a resource in the long term. Whose responsibility is it to maintain the public repositories of data, animals and cells on which science depends? We will then go onto look at existing economic models for resource pricing, and with an eye on the future, what happens to resources which contain valuable data but are not viably funded.

The outcome of the meeting will be a published report in the literature to stimulate community discussion.


Wednesday 11th November

09:00 – 09:15
Paul Schofield, CASIMIR Coordinator, Cambridge University, UK

Session 1: Sustainability of Animal and other Bioresources
Chair, Nadia Rosenthal

09:15 – 09:35
Experience of cost recovery models in Bioresource Centres
Tom Weaver, Director, Mary Lyon Centre, MRC Harwell,Oxford, UK.

09:35 – 09:55
Michael Hagn, Helmholtz München, Germany.

09:55 – 10:15
Infrafrontier: the European research infrastructure for phenotyping and archiving of model mammalian genomes
Martin Hrabe de Angelis, Helmholtz München, Germany.

10:15 – 10:35
Disruptive innovation in the biorepository world...a case study
Kent Lloyd, Department of Anatomy, Physiology & Cell Biology, UC Davis, USA

11:05 – 11:25
The Riken Bioresource Centre
Atsushi Yoshiki, Riken BRC, Japan.

11:25 - 11:45
Experience with the RZPD
Johannes Maurer, ImaGenes GmbH, Berlin, Germany.

11:45 - 12:05
The Toronto Centre for Phenogenomics
Colin McKerlie, TCP, Toronto, Canada.

12:05 – 12:25
Panel Discussion

Session 2: Databases - Experience of sustainability in databases
Chair, John Hancock

13:30 – 13:50
Duncan Davidson, MRC Human Genetics Unit, Edinburgh

13:50 – 14:10
Janan Eppig, Mouse Genome Informatics, The Jackson Laboratory

14:10 – 14:30
Array Express
Helen Parkinson, European Bioinformatics Institute, UK.

14:30 – 15:00
Panel Discussion

Session 3: Business models for Public and private sector funding
Chair, Tom Weaver

We will start with a series of short talks highlighting experiences from public and private sector as to existing models, opportunities and challenges going forward.

We will then have a panel discussion in which we will apply the ideas raised in a brainstorm around the following case study: An international consortium is being planned in which genotype/phenotype data is collected across many thousand mutant mice. The resulting data will be analyzed and placed into the public domain through a dedicated data centre. If such a program was funded, what would be the major considerations for ensuring the long-term sustainability of such an infrastructure? Who benefits and should they be expected to contribute towards resource sustainability, and if so, how? Would a publicly available data resource like this have “commercial” value, and can/should this value be exploited to support its long-term maintenance and development? What role can private companies play in supporting such an initiative?

15:30 – 15:50
Gordon Baxter, CEO Biowisdom, Cambridge, UK.

15:50 – 16:10
"Sage" an open access, integrative bionetwork
Stephen Friend, CEO SAGE Bionetworks, Seattle, USA.

16:10 – 16:30
Funding crisis at TAIR - The Arabidopsis Information Resource
Eva Huala, Director, The Arabidopsis Information Resource, Carnegie Institution of Washington, Stanford, USA

16:30 – 16:50
Alan Bridge, UniProt, Swiss Institute of Bioinformatics, Geneva, Switzerland.

16:50 – 17:10
The NERC environmental bioinformatics centre
Dawn Field, Chris Taylor, NERC Centre for Ecology and Hydrology, Oxford, UK

17:10 – 17:40
Panel Discussion

Thursday 12th November

09:00 – 09:10
Paul Schofield, CASIMIR Coordinator, Cambridge University, UK

Session 4: Models for resource pricing and sustainability
Chair, Paul Schofield

09:10 – 09:30
Public or Private Economies of Knowledge
Mark Harvey, Centre for Research on Economic Sociology and Innovation (CRESI), University of Essex, UK.

09:30 – 09:50
The BBSRC Bioinformatics and Biological Resources Fund
Amanda Collis, BBSRC, UK.

09:50 – 10:10
Economic models for resource pricing
Michael Kuczynski, Cambridge University, UK.

10:40 – 11:00
Curating Curated Databases
Peter Buneman, Director, Digital Curation Centre, University of Edinburgh, UK.

11:00 – 11:20
Overview of bio-repositories and databases funded by the European Commission through the various framework programmes
Christian Desaintes, Scientific Officer - Genomics and Systems Biology, European Commission.

11:20 – 11:40
Panel Discussion

11:40 – 12:30
Final discussion

Additional material:

participants list.pdf





Hrabe de Angelis.pdf










Field Taylor.pdf




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